×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
Synchronous Onset of Breast and Pancreatic Cancers: Results of Germline and Somatic Genetic Analysis.
27721756
2019
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Neoplastic Syndromes, Hereditary
0.130
GeneticVariation
CLINVAR
Genomic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy.
29398457
2019
×
Entrez Id:
23164
Gene Symbol:
MPRIP
MPRIP
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Clinical Features, Genetics and Potential Therapeutic Approaches for Birt-Hogg-Dubé Syndrome.
26581862
2019
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Characterization of the c.793-1G > A splicing variant in CHEK2 gene as pathogenic: a case report.
31349801
2019
×
Entrez Id:
201163
Gene Symbol:
FLCN
FLCN
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Clinical Features, Genetics and Potential Therapeutic Approaches for Birt-Hogg-Dubé Syndrome.
26581862
2019
×
Entrez Id:
5979
Gene Symbol:
RET
RET
Neoplastic Syndromes, Hereditary
0.200
CausalMutation
CLINVAR
Genotype-specific progression of hereditary medullary thyroid cancer.
29656518
2018
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Neoplastic Syndromes, Hereditary
0.170
GeneticVariation
CLINVAR
TP53 germline and somatic mutations in a patient with fibrolamellar hepatocellular carcinoma.
28477317
2018
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Neoplastic Syndromes, Hereditary
0.170
GeneticVariation
CLINVAR
Clinical characteristics and registry-validated extended pedigrees of germline TP53 mutation carriers in Denmark.
29324801
2018
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Neoplastic Syndromes, Hereditary
0.160
CausalMutation
CLINVAR
A longitudinally extensive myelopathy associated with multiple spinal arteriovenous fistulas in a patient with Cowden syndrome: a case report.
26795104
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
The yield of targeted genotyping for the recurring mutations in BRCA1/2 in Israel.
29086229
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
The BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant: breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium.
28490613
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Gene-panel testing of breast and ovarian cancer patients identifies a recurrent RAD51C duplication.
28802053
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations.
29446198
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
BRCA1 and BRCA2 germline variants in breast cancer patients from the Republic of Macedonia.
29335924
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Is there a genetic anticipation in breast and/or ovarian cancer families with the germline c.3481_3491del11 mutation?
28493033
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
BRCA1 and BRCA2 mutation spectrum - an update on mutation distribution in a large cancer genetics clinic in Norway.
29339979
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Mutations in context: implications of BRCA testing in diverse populations.
28918466
2018
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Clinical and Genetic Implications of DNA Mismatch Repair Deficiency in Biliary Tract Cancers Associated with Lynch Syndrome.
29238914
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study.
29337092
2018
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Comprehensive analysis of the MLH1 promoter region in 480 patients with colorectal cancer and 1150 controls reveals new variants including one with a heritable constitutional MLH1 epimutation.
29472279
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
BRCA1 and BRCA2 mutation spectrum - an update on mutation distribution in a large cancer genetics clinic in Norway.
29339979
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Genetic and clinical characteristics in Japanese hereditary breast and ovarian cancer: first report after establishment of HBOC registration system in Japan.
29176636
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Characterization of mutations in BRCA1/2 and the relationship with clinic-pathological features of breast cancer in a hereditarily high-risk sample of chinese population.
29435039
2018
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
High prevalence of deleterious BRCA1 and BRCA2 germline mutations in arab breast and ovarian cancer patients.
29297111
2018
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Neoplastic Syndromes, Hereditary
0.130
CausalMutation
CLINVAR
High prevalence of deleterious BRCA1 and BRCA2 germline mutations in arab breast and ovarian cancer patients.
29297111
2018